Cryo-EM epitope mapping: SARS-CoV-2 spike protein antibodies

June 12,2024

Learn from recent drug discovery case studies that leverage cutting-edge cryo-EM workflow advancements and technologies

Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection

Viruses, Free Full-Text

Computational epitope map of SARS-CoV-2 spike protein

An overview of methods for the structural and functional mapping of epitopes recognized by anti-SARS-CoV-2 antibodies - RSC Chemical Biology (RSC Publishing) DOI:10.1039/D1CB00169H

High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination

Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses

Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies - ScienceDirect

In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM

Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines

Integrated Biophysical Modeling of the SARS-CoV-2 Spike Protein Binding and Allosteric Interactions with Antibodies

Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection, Journal of Biomedical Science